Publications

Loughran G , Andreev DE , Terenin IM , Namy O , Mikl M , Yordanova MM, Mcmanus CJ, Firth AE, Atkins JF, Fraser CS, Ignatova Z, Iwasaki S, Kufel J, Larson O, Leidel SA, Mankin AS, Mariotti M, Tanenbaum ME, Topsirovic I, Vázquez-Laslop N, Viero G, Caliskan N, Chen Y, Clark PL, Dinman JD, Farabaugh PJ, Gilbert WV, Ivanov P , Kieft JS, Mühlemann O, Sachs MS, Shatsky IN, Sonenberg S, Steckelberg AL, Willis AE, Woodside MT, Valasek SL, Dmitriev SE, Baranov PV. “Guidelines for minimal reporting requirements, design and interpretation of experiments involving the use of eukaryotic dual gene expression reporters (MINDR)” hal-04395528 (Preprint)

Korn SM, Sharma S, Steckelberg, AL. “The ART of RNAylation: covalent RNA–protein linkage in bacteriophage infection.” Trends in Biochemical Sciences November 2023, doi:https://doi.org/10.1016/j.tibs.2023.10.011

Dorrity TJ, Shin H, Wiegand KA, Aruda J, Closser M, Jung E, Gertie JA, Leone A, Polfer R, Culbertson B, Yu L, Wu C, Ito T, Huang Y, Steckelberg AL, Wichterle H, Chung H. “Long 3′ UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation.” Science Immunology Oct 2023 doi: 10.1126/sciimmunol.adg29

Maurina, S. F.*, O'Sullivan, J. P.*, Sharma, G.*, Pineda Rodriguez, D. C., MacFadden, A., Cendali, F., Henen, M. A., Voegeli B. Kieft, J. S., Glasgow, A., & Steckelberg, A. L. “An evolutionarily conserved strategy for ribosome binding and inhibition by β-coronavirus non-structural protein 1.” Journal of Molecular Biology. September 2023, doi: 10.1016/j.jmb.2023.168259

Khan JA, Loughran G, Steckelberg AL, Brown K, Kiniry SJ, Stewart H, Baranov PV, Kieft JS, Firth AE, Atkins JF. “Evaluating −1 PRF in CCR5 with translational reporter assays.” Nature 604, E16–E23 (2022)

Publications before 2021:

Steckelberg AL*, Vicens Q*, Costantino DA, Nix JC, Kieft JS. “The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold.” RNA August 26, 2020, doi: 10.1261/rna.076224.120

Jones RA, Steckelberg AL, Szucs MJ, Akiyama BM, Vicens Q, Kieft JS. “Different tertiary interactions create the same important 3D features in a divergent flavivirus xrRNA.” RNA 2021 Jan;27(1):54-65. doi: 10.1261/rna.077065.120

Steckelberg AL*, Vicens Q*, Kieft JS. “Exoribonuclease-Resistant RNAs Exist within both Coding and Noncoding Subgenomic RNAs.” MBio. 2018 Dec 18;9(6)

Boehm V, Britto-Borges T, Steckelberg AL, Singh KK, Gerbracht JV, Gueney E, Blazquez L, Altmüller J, Dieterich C, Gehring NH.  “Exon junction complexes suppress spurious splice sites to safeguard transcriptome integrity” Mol Cell. 2018 Nov 1;72(3):482-495

Steckelberg AL, Akiyama BM, Costantino DA, Sit TL, Nix JC, Kieft JS. "A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure." Proc Natl Acad Sci USA 2018 Jun 19;115(25):6404-6409

Gromadzka AM, Steckelberg AL, Singh KK, Hofmann K, Gehring NH. “A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAs.” Nucleic Acids Res. 2016 Mar 18;44(5):2348-61

Steckelberg AL, Altmueller J, Dieterich C, Gehring NH. “CWC22-dependent pre-mRNA splicing and eIF4A3 binding enables global deposition of exon junction complexes.” Nucleic Acids Res. 2015 May 19;43(9):4687-700

Steckelberg AL, Gehring NH. “Studying the composition of mRNPs in vitro using splicing-competent cell extracts.” Methods. 2014 Feb;65(3):342-9

Burgute BD, Peche VS, Steckelberg AL, Glöckner G, Gaßen B, Gehring NH, Noegel AA. “NKAP is a novel RS-related protein that interacts with RNA and RNA binding proteins.” Nucleic Acids Res. 2014 Mar;42(5):3177-93

Steckelberg AL, Boehm V, Gromadzka AM, Gehring NH. “CWC22 connects pre-mRNA splicing and exon junction complex assembly.” Cell Rep. 2012 Sep 27;2(3):454-61

*equal contribution